The Drug Interaction Knowledge Base

The Drug Interaction Knowledge Base (DIKB) is clinically-oriented, evidence-based, knowledge base designed to support pharmacoepidemiology and clinical decision support. It contains quantitative and qualitative assertions about drug mechanisms and pharmacokinetic drug-drug interactions for over 60 drugs; primarily psychotropics and HMG-CoA reductase inhibitors (statins). The linked-data version of the DIKB was implemented using emerging practices from the W3C HCLS SIG Linking Open Drug Data and Scientific Discource task forces.